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Blog Articles Tagged With   "enzyme"
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Another Alzheimer's Compound Goes Down
In In the Pipeline - Posted 4 days ago
I was mentioning the gamma secretase enzyme around here just the other day as a longstanding target for Alzheimer's therapy. I remember the periodduri...
Tags: enzyme phase
Funding in the EU: The Simple Way
In In the Pipeline - Posted 1 week ago
Today I have the second part of the guest commentary from Zurich's Dr. Theo Wallimann on research funding in Europe. Today he advances his proposal fo...
Tags: enzyme protein
(No) Anarchy in the EU: A Report From Inside
In In the Pipeline - Posted 1 week ago
My post a few days ago on research in the EU, quoting a letter to Nature from Dr. Theo Wallimann in Zurich, started off a long comment thread. And now...
Tags: enzyme
Auroral Activity
In In the Pipeline - Posted 1 week ago
If you go to the med-chem or pharmacology literature databases and type Aurora kinase , you'd better stand back. A geyser of publications will come s...
Tags: enzyme
Protecting Amyloid's Parent?
In In the Pipeline - Posted 2 weeks ago
Let s start from first principles: most drugs mess something up. More elegantly, most drugs inhibit some enzyme s activity or block some receptor ...
Tags: disease enzyme protein
We recently encountered a problem that s (unfort
In In the Pipeline - Posted 4 weeks ago
We recently encountered a problem that s (unfortunately) a rather common one. An enzyme assay turned up an interesting hit compound, with some chara...
Tags: enzyme
Up Close and Personal
In In the Pipeline - Posted 6 weeks ago
Something that s come up in the last few posts around here is the way that we chemists think about the insides of enzymes. It s a tricky subject, ...
Tags: enzyme phase protein
Disabling mouse enzyme increases fertility
In Science Blog - Think. It's not illegal yet. - Posted 7 weeks ago
Changing the sugars attached to a hormone produced in the pituitary gland increased fertility levels in mice nearly 50 percent, a research group at Wa...
Tags: enzyme
Research reveals workings of anti-HIV drugs
In Science Blog - Think. It's not illegal yet. - Posted 7 weeks ago
Using ingenious molecular espionage, scientists have found how a single key enzyme, seemingly the Swiss Army knife in HIV s toolbox, differentiates ...
Tags: enzyme
Aldagen Files for IPO Despite Tough Market
In SeekingAlpha ETFs - Posted 7 weeks ago
On the same day that Elixir Pharmaceuticals canned its IPO plans citing tough market conditions, Aldagen filed an S-1 expecting to raise as much as $8...
Tags: biotech enzyme ipo phase
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