Visit In the Pipeline

Auroral Activity

Posted on June 23, 2008

If you go to the med-chem or pharmacology literature databases and type Aurora kinase , you'd better stand back. A geyser of publications will come spraying out, most of them having to do with Aurora A and/or Aurora B as possible targets for cancer therapy. These enzymes are involved in different phases of cell division, among other things, and a lot of evidence points to them as key players in several cancer lines. There are a number of inhibitors compounds known for them as well, in various stages of development, some of which are selective and some of which hit both to different degrees. A...

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